First report of prevalence of non‐syndromic hereditary prosopagnosia (HPA)

@article{Kennerknecht2006FirstRO,
  title={First report of prevalence of non‐syndromic hereditary prosopagnosia (HPA)},
  author={Ingo Kennerknecht and Thomas Grueter and Brigitte Welling and Sebastian Wentzek and J{\"u}rgen Horst and Stephen D. Edwards and Martina Grueter},
  journal={American Journal of Medical Genetics Part A},
  year={2006},
  volume={140A}
}
Acquired prosopagnosia (PA) is a rare condition after, for example, a stroke or brain injury. [] Key Method Following a questionnaire-based screening in local secondary schools and at our medical faculty, candidates suspicious for PA underwent a semi-structured interview followed by examinations of first degree relatives. Among 689 local pupils and medical students of our university we found 17 with congenital PA. This corresponds to a prevalence rate of 2.47% (95% CI 1.31-3.63). The frequency is among the…

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...

References

SHOWING 1-10 OF 41 REFERENCES

Hereditary Prosopagnosia: the First Case Series

A Fifteen Year Follow-Up of a Case of Developmental Prosopagnosia

DEVELOPMENTAL PROSOPAGNOSIA IN ASPERGER SYNDROME: PRESENTATION AND DISCUSSION OF AN INDIVIDUAL CASE

  • I. Kracke
  • Psychology
    Developmental medicine and child neurology
  • 1994
TLDR
The case of a young man is presented who initially appeared to be quite normal and very intelligent, if somewhat immature, but closer investigation revealed definite autistic features of the Asperger type, and both conditions ran in the family in a milder form.

Developmental Prosopagnosia: A Review

TLDR
It is suggested that developmental prosopagnosia is not a unitary condition but rather consists of different subforms that can be dissociated on the grounds of functional impairments.

Severe Developmental Prosopagnosia in a Child With Superior Intellect

  • R. JonesD. Tranel
  • Psychology
    Journal of clinical and experimental neuropsychology
  • 2001
TLDR
A novel finding was that the childs covert recognition of familiar faces based on an autonomic index was normal, suggesting that as in some adult-onset cases, the brain is capable of acquiring some information about familiar faces, even without conscious recognition.

Prosopagnosia in a preschool child with Asperger syndrome.

TLDR
Although impairment in reciprocal social interaction in individuals with Asperger syndrome is closely correlated to their impaired perceptional abilities in non-verbal communication, especially facial expression, overt prosopagnosia seems to be a rare neuropsychological symptom in persons with autistic disorders.

Congenital Visual Agnosia and Prosopagnosia in a Child: A Case Report

Congenital prosopagnosia: face-blind from birth

Contributions to Neuropsychological Assessment

TLDR
This cornucopia will be coveted and dipped into by those neurologists with a special interest in abnormal movement disorders, but who would not consider themselves to have a research interest in tremor.

A forkhead-domain gene is mutated in a severe speech and language disorder

TLDR
It is suggested that the gene FOXP2, which encodes a putative transcription factor containing a polyglutamine tract and a forkhead DNA-binding domain, is involved in the developmental process that culminates in speech and language.