First report of prevalence of non‐syndromic hereditary prosopagnosia (HPA)

  title={First report of prevalence of non‐syndromic hereditary prosopagnosia (HPA)},
  author={Ingo Kennerknecht and Thomas Grueter and Brigitte Welling and Sebastian Wentzek and J{\"u}rgen Horst and Stephen D. Edwards and Martina Grueter},
  journal={American Journal of Medical Genetics Part A},
Acquired prosopagnosia (PA) is a rare condition after, for example, a stroke or brain injury. [] Key Method Following a questionnaire-based screening in local secondary schools and at our medical faculty, candidates suspicious for PA underwent a semi-structured interview followed by examinations of first degree relatives. Among 689 local pupils and medical students of our university we found 17 with congenital PA. This corresponds to a prevalence rate of 2.47% (95% CI 1.31-3.63). The frequency is among the…

Prevalence of hereditary prosopagnosia (HPA) in Hong Kong Chinese population

This is the first systematic screening for HPA in a defined population of ethnic Chinese and takes a detailed family history of four index prosopagnosic persons and was able to further investigate the families of four probands.

Hereditary prosopagnosia (HPA): the first report outside the Caucasian population

The term non-syndromic hereditary PA is introduced for the congenital form of a monosymptomatic or isolated PA, best described by autosomal-dominant inheritance in the more than 50 families investigated.

Congenital prosopagnosia--a common hereditary cognitive dysfunction in humans.

The segregation patterns derived from 39 families are compatible with autosomal dominant inheritance and mutation(s) in one gene are sufficient for manifestation of the phenotype.

Hereditary Prosopagnosia: the First Case Series

Cognitive heterogeneity in genetically based prosopagnosia: a family study.

The results indicate that genetically based CP is not a single trait but a cluster of related subtypes, since the pattern of impairments to specific components of the face-processing system varies in individuals belonging to the same family.

Neuro-ophthalmological findings in patients with acquired prosopagnosia

  • D. Schmidt
  • Medicine, Psychology
    Graefe's Archive for Clinical and Experimental Ophthalmology
  • 2014
Autopsy findings of subjects with acquired PA showed extensive cerebral damage to the occipitotemporal lobes.

On the prevalence of congenital amusia

It is concluded that although the MBEA has shown to be a valuable diagnostic tool, caution is warranted against attributing meaning to the reported 4% rate of congenital amusia that is so widely cited in the literature.

Interrogating an ICD-coded electronic health records database to characterize the epidemiology of prosopagnosia

A large database of more than 7.5 million de-identified electronic health records from patients who received care at major academic health centers and Federally Qualified Health Centers in New York City revealed elevated frequency of prosopagnosia diagnosis for individuals who carried certain comorbid conditions, such as personality disorder, depression, epilepsy, and anxiety.

The Definition and Diagnosis of Developmental Prosopagnosia

An overview of the current challenges that face research into developmental prosopagnosia is presented and a series of papers that attempt to further the understanding of the condition's characteristics are introduced.



Hereditary Prosopagnosia: the First Case Series

A Fifteen Year Follow-Up of a Case of Developmental Prosopagnosia


  • I. Kracke
  • Psychology
    Developmental medicine and child neurology
  • 1994
The case of a young man is presented who initially appeared to be quite normal and very intelligent, if somewhat immature, but closer investigation revealed definite autistic features of the Asperger type, and both conditions ran in the family in a milder form.

Developmental Prosopagnosia: A Review

It is suggested that developmental prosopagnosia is not a unitary condition but rather consists of different subforms that can be dissociated on the grounds of functional impairments.

Severe Developmental Prosopagnosia in a Child With Superior Intellect

  • R. JonesD. Tranel
  • Psychology
    Journal of clinical and experimental neuropsychology
  • 2001
A novel finding was that the childs covert recognition of familiar faces based on an autonomic index was normal, suggesting that as in some adult-onset cases, the brain is capable of acquiring some information about familiar faces, even without conscious recognition.

Prosopagnosia in a preschool child with Asperger syndrome.

Although impairment in reciprocal social interaction in individuals with Asperger syndrome is closely correlated to their impaired perceptional abilities in non-verbal communication, especially facial expression, overt prosopagnosia seems to be a rare neuropsychological symptom in persons with autistic disorders.

Congenital Visual Agnosia and Prosopagnosia in a Child: A Case Report

Congenital prosopagnosia: face-blind from birth

Contributions to Neuropsychological Assessment

This cornucopia will be coveted and dipped into by those neurologists with a special interest in abnormal movement disorders, but who would not consider themselves to have a research interest in tremor.

A forkhead-domain gene is mutated in a severe speech and language disorder

It is suggested that the gene FOXP2, which encodes a putative transcription factor containing a polyglutamine tract and a forkhead DNA-binding domain, is involved in the developmental process that culminates in speech and language.