First report of human immunodeficiency virus transmission via an RNA-screened blood donation.

@article{Delwart2004FirstRO,
  title={First report of human immunodeficiency virus transmission via an RNA-screened blood donation.},
  author={Eric L Delwart and Norman D Kalmin and Terreia S. Jones and D. J. Ladd and Brian Foley and Leslie H. H. Tobler and R C P Tsui and Michael P. Busch},
  journal={Vox sanguinis},
  year={2004},
  volume={86 3},
  pages={171-7}
}
BACKGROUND AND OBJECTIVES Blood banks in the USA have recently introduced minipool nucleic acid amplification testing (MP-NAT) of blood products to reduce the transmission of human immunodeficiency virus (HIV) and hepatitis C virus (HCV) by transfusions. However, MP-NAT is limited in its ability to detect preseroconversion samples with very low viral RNA loads. MATERIALS AND METHODS To determine whether a red blood cell unit, from an MP-NAT-negative donation, transmitted HIV when transfused… CONTINUE READING

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