First report of an Asian family with hemoglobin Evans [α2 62 (E11) Val → Met]

  title={First report of an Asian family with hemoglobin Evans [α2 62 (E11) Val → Met]},
  author={S. Ishimaru and Y. Saito and Y. Yokokawa and Y. Yuza and T. Kaneko},
  journal={Pediatrics International},
  pages={301 - 303}
  • S. Ishimaru, Y. Saito, +2 authors T. Kaneko
  • Published 2016
  • Medicine
  • Pediatrics International
  • Hemoglobin Evans is an unstable variant caused by a single nucleotide mutation that produces a valine‐to‐methionine substitution at residue 62 of the α‐globin chain. It has not been reported in the Asian population and only three cases have been reported worldwide. We diagnosed a Japanese boy with chronic hemolytic anemia with hemoglobin Evans after genetic testing. This is the first familial case of hemoglobin Evans in an Asian population. 
    1 Citations

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    [Hemolytic anemia due to hemoglobin Evans in an Argentinean family].
    • 4
    • PDF
    A Simple Method for the Detection of Unstable Haemoglobins
    • 452
    Aplastic crisis revealing the diagnosis of Hb Evans[α2 62 (E11) Val→Met] in a Hispanic kindred: Case report and review
    • Hemoglobin
    • 2007
    Abnormal hemoglobinopathy
    • Shounika Rinsho
    • 1998
    [Mass screening method of abnormal hemoglobin by isoelectric focusing (author's transl)].
    • 4
    A simple method for detection of unstable hemoglobins
    • Br. J. Haematol
    • 1972