First-phase insulin secretion has limited impact on postprandial glycemia in subjects with type 2 diabetes: correlations between hyperglycemic glucose clamp and meal test.

Abstract

BACKGROUND Lack of first-phase insulin (INS) secretion is regarded as causative for high postprandial glucose excursions in subjects with type 2 diabetes. We aimed to determine the impact of early INS secretion on postprandial glycemia. METHODS Twenty subjects with type 2 diabetes (age 54 +/- 8 years, body mass index 28.7 +/- 2.7 kg/m(2) [mean +/- SD… (More)
DOI: 10.1089/dia.2009.0103

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@article{Rave2010FirstphaseIS, title={First-phase insulin secretion has limited impact on postprandial glycemia in subjects with type 2 diabetes: correlations between hyperglycemic glucose clamp and meal test.}, author={Klaus M Rave and Patricia N. Sidharta and J Gertjan Dingemanse and L. Heinemann and Kerstin Roggen}, journal={Diabetes technology & therapeutics}, year={2010}, volume={12 2}, pages={117-23} }