First occurrence of a Pseudomonas aeruginosa isolate in the United States producing an IMP metallo-beta-lactamase, IMP-18.

@article{Hanson2006FirstOO,
  title={First occurrence of a Pseudomonas aeruginosa isolate in the United States producing an IMP metallo-beta-lactamase, IMP-18.},
  author={Nancy D Hanson and A B M Bayezid Hossain and Larry Buck and Ellen Smith Moland and Kenneth S. Thomson},
  journal={Antimicrobial agents and chemotherapy},
  year={2006},
  volume={50 6},
  pages={2272-3}
}
Metallo-lactamases hydrolyze most -lactam antibiotics except aztreonam. Therefore, many pathogens that produce these enzymes at high levels are resistant to the majority of -lactam antibiotics, including the carbapenems. The first report of an imported metallo-lactamase described a Pseudomonas aeruginosa isolate obtained from a Japanese patient in 1988 (6). Since then, the occurrence of mobile genetic elements encoding metallo-lactamases has extended beyond P. aeruginosa to include many types… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

Similar Papers

Loading similar papers…