First-line treatment of advanced ovarian cancer: current research and perspectives

  title={First-line treatment of advanced ovarian cancer: current research and perspectives},
  author={C. Marchetti and C. Pisano and G. Facchini and G. Bruni and Francesca Paola Magazzino and S. Losito and S. Pignata},
  journal={Expert Review of Anticancer Therapy},
  pages={47 - 60}
  • C. Marchetti, C. Pisano, +4 authors S. Pignata
  • Published 2010
  • Medicine
  • Expert Review of Anticancer Therapy
  • Epithelial ovarian cancer is the fourth biggest cause of cancer-related death in women. Over recent decades, improvements have been made in treatment outcome in terms of response rate and survival. To date, intensive surgical staging and cytoreduction, followed by primary chemotherapy with the carboplatin–paclitaxel regimen, are considered the gold standard for the management of this disease. Nevertheless, despite good initial response to systemic therapy after optimal debulking surgery, the… CONTINUE READING
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