First-line intra-arterial chemotherapy (IAC) with epirubicin and mitoxantrone in locally advanced breast cancer.

  title={First-line intra-arterial chemotherapy (IAC) with epirubicin and mitoxantrone in locally advanced breast cancer.},
  author={G. Fiorentini and D. Tsetis and P. Bernardeschi and C. Varveris and S. Rossi and A. Kalogeraki and E. Athanasakis and P. Dentico and P. Kanellos and M. Biancalani and S. Almarashdah and G. Zacharioudakis and Z. Saridaki and G. Chalkiadakis and E. Xynos and O. Zoras},
  journal={Anticancer research},
  volume={23 5b},
  • G. Fiorentini, D. Tsetis, +13 authors O. Zoras
  • Published 2003
  • Medicine
  • Anticancer research
  • BACKGROUND Approximately 20% of patients with breast cancer present with locally advanced disease without distant metastases. This phase II double-center trial aimed at investigating the activity of epirubicin (Farmorubicin)--mitoxantrone (Onkotrone/Novantrone) combination as first-line intra-arterial chemotherapy (IAC) in locally advanced breast cancer patients. PATIENTS AND METHODS Thirty-six patients with locally advanced disease and no prior exposure to anthracyclines received the… CONTINUE READING
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