First ketene cycloaddition approach to (±)-junionone.

@article{Erden2016FirstKC,
  title={First ketene cycloaddition approach to (±)-junionone.},
  author={Ihsan Erden and Samuel E Watson},
  journal={Tetrahedron letters},
  year={2016},
  volume={57 2},
  pages={237-238}
}
Junionone is the first monocyclic cyclobutane monoterpenoid isolated from a plant. Of the existing four syntheses of this compound, none employs a ketene cycloaddition to construct the four-membered ring. Herein, we report the first total synthesis of junionone that features a ketene cycloaddition for the synthesis of this compound, starting from the… CONTINUE READING