First insights in the metabolism of phosphate flame retardants and plasticizers using human liver fractions.

@article{Eede2013FirstII,
  title={First insights in the metabolism of phosphate flame retardants and plasticizers using human liver fractions.},
  author={Nele van den Eede and Walid Maho and Claudio A Erratico and Hugo M. Neels and Adrian Covaci},
  journal={Toxicology letters},
  year={2013},
  volume={223 1},
  pages={
          9-15
        }
}
Phosphate flame retardants and plasticizers (PFRs) are additives used in a wide range of polymers. Important representatives, such as tris(2-butoxyethyl) phosphate (TBOEP), triphenyl phosphate (TPHP), tris(2-chloroethyl) phosphate (TCEP), tris(1-chloro-2-propyl) phosphate (TCIPP), tris(1,3-dichloro-2-propyl) phosphate (TDCIPP), have been found in the indoor environment at high levels. Biotransformation of these PFRs needs to be investigated because it can be a major determinant of their… CONTINUE READING
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