First insight into CD59-like molecules of adult Fasciola hepatica.

@article{Shi2014FirstII,
  title={First insight into CD59-like molecules of adult Fasciola hepatica.},
  author={Yunliang Shi and Hayley Toet and Vignesh Rathinasamy and Neil David Young and Robin B. Gasser and Travis Beddoe and Weiyi Huang and Terry W. Spithill},
  journal={Experimental parasitology},
  year={2014},
  volume={144},
  pages={
          57-64
        }
}
  • Yunliang Shi, Hayley Toet, +5 authors Terry W. Spithill
  • Published in Experimental parasitology 2014
  • Biology, Medicine
  • The present study focussed on investigating CD59-like molecules of Fasciola hepatica. A cDNA encoding a CD59-like protein (termed FhCD59-1) identified previously in the membrane fraction of the F. hepatica tegument was isolated. This homologue was shown to encode a predicted open reading frame (ORF) of 122 amino acids (aa) orthologous to human CD59 with a 25 aa signal peptide, a mature protein containing 10 cysteines and a conserved CD59/Ly-6 family motif "CCXXXXCN". An analysis of cDNAs from… CONTINUE READING

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