First indication for a functional CRISPR/Cas system in Francisella tularensis.

@article{Schunder2013FirstIF,
  title={First indication for a functional CRISPR/Cas system in Francisella tularensis.},
  author={Eva Schunder and Kerstin Rydzewski and Roland Grunow and Klaus Heuner},
  journal={International journal of medical microbiology : IJMM},
  year={2013},
  volume={303 2},
  pages={
          51-60
        }
}
  • Eva Schunder, Kerstin Rydzewski, +1 author Klaus Heuner
  • Published in
    International journal of…
    2013
  • Biology, Medicine
  • Francisella tularensis is a zoonotic agent and the subspecies novicida is proposed to be a water-associated bacterium. The intracellular pathogen F. tularensis causes tularemia in humans and is known for its potential to be used as a biological threat. We analyzed the genome sequence of F. tularensis subsp. novicida U112 in silico for the presence of a putative functional CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR-associated) system. CRISPR/Cas systems are… CONTINUE READING

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