First human case report of sepsis due to infection with Streptococcus suis serotype 31 in Thailand

  title={First human case report of sepsis due to infection with Streptococcus suis serotype 31 in Thailand},
  author={Rujirat Hatrongjit and Anusak Kerdsin and Marcelo Gottschalk and Dan Takeuchi and Shigeyuki Hamada and Kazunori Oishi and Yukihiro Akeda},
  journal={BMC Infectious Diseases},
BackgroundStreptococcus suis is a zoonotic pathogen that causes invasive infections in humans and pigs. It has been reported that S. suis infection in humans is mostly caused by serotype 2. However, human cases caused by other serotypes have rarely been reported. This is the first report of a human case of infection with S. suis serotype 31 in Thailand.Case presentationA 55-year-old male alcohol misuser with liver cirrhosis was admitted with sepsis to a hospital in the Central Region of… 

Human infection caused by Streptococcus suis serotype 2 in China: report of two cases and epidemic distribution based on sequence type

The results enhanced the understanding of the ability to cause life-threatening infections in humans and the distribution and evolution of the S. suis in China and several novel STs were successfully discovered in different provinces.

Human Streptococcus suis Infections in Thailand: Epidemiology, Clinical Features, Genotypes, and Susceptibility

  • A. Kerdsin
  • Medicine, Biology
    Tropical medicine and infectious disease
  • 2022
Reducing S. suis incidence in Thailand requires a multidimensional approach, with combined efforts from the government and public health sectors through policy, regulations, education, and active surveillance.

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This investigation demonstrates that multi-drug resistant zoonotic lineages of S. suis which pose a threat to human health continue to emerge.

Streptococcus suis: An Underestimated Emerging Pathogen in Hungary?

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Genotypic Comparison between Streptococcus suis Isolated from Pigs and Humans in Thailand

It is suggested that pathogenic strains of S. suis are a risk factor for occupational exposure to pigs or the consumption of raw pork products and food safety, hygiene, and health education should be encouraged to reduce the risk group.

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Pyogenic zoonotic streptococcal infections are neglected zoonoses which have increasingly been reported, especially in Asia, and can produce a wide variety of invasive diseases that mimic clinical

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Streptococcus suis serotype 9 endocarditis and subsequent severe meningitis in a growing pig despite specific bactericidal humoral immunity

Endocarditis induced by S. suis infection might develop and persist despite the presence of high specific bactericidal activity in the blood, and severe leptomeningitis is a putative sequela of such an endocarditis.

Meningitis due to Streptococcus suis in Two Patients with Occupational Exposure from Northeastern Brazil

Two cases of meningitis related to S. suis with occupational exposure from the Ceará state, northeastern Brazil are reported.

Fatal Septic Meningitis in Child Caused by Streptococcus suis Serotype 24

A rare case of S. suis serotype 24 infection in a child is reported.



A human case of Streptococcus suis infection caused by an unencapsulated strain

This work has identified the first human S. suis infection caused by an unencapsulated strain in a patient with liver cirrhosis, attributable to a mutation of the cps gene.

Streptococcus suis Infection as a Cause of Severe Illness: 2 Cases from Croatia

One patient suffered an abrupt and severe illness, with septic shock leading to multiorgan failure and death, whereas the other presented with purulent meningitis and deafness, in contrast to previous reports indicating an association between human infection and S. suis type 2.

Streptococcus suis, an important pig pathogen and emerging zoonotic agent—an update on the worldwide distribution based on serotyping and sequence typing

This review presents the worldwide distribution of serotypes and sequence types (STs), as determined by multilocus sequence typing, for pigs and humans between 2002 and 2013 and if these differences can be associated with specific serotypes or STs.

Loss of capsule among Streptococcus suis isolates from porcine endocarditis and its biological significance.

Results suggest that loss of capsular production is beneficial to S. suis in the course of infective endocarditis.

Non‐encapsulated strains reveal novel insights in invasion and survival of Streptococcus suis in epithelial cells

Novel evidence is revealed that S. suis exhibits a broad variety of virulence‐associated features depending on genetic variation and regulation.

Development of a Multilocus Sequence Typing Scheme for the Pig Pathogen Streptococcus suis: Identification of Virulent Clones and Potential Capsular Serotype Exchange

A multilocus sequence typing (MLST) scheme for S. suis is described, highlighting that the serotype can often be a poor indicator of genetic relatedness between S. Suis isolates and suggesting that capsular genes may be moving horizontally through the S.Suis population.

Development of Multiplex PCR Assays for the Identification of the 33 Serotypes of Streptococcus suis

The multiplex PCR assays developed in this study provide a rapid and specific method for molecular serotyping of S .

Cell surface characteristics of nontypeable isolates of Streptococcus suis.

The seven nontypeable strains of S. suis isolated from infected animals demonstrated a stronger capacity to adhere to a fibronectin-coated polystyrene surface than the serotype 2 isolates, and showed the capacity to form a biofilm while serotype 1 isolates were unable to do so.

Identification and characterization of IgA1 protease from Streptococcus suis.