First human Cerenkography

@article{Spinelli2013FirstHC,
  title={First human Cerenkography},
  author={Antonello Enrico Spinelli and Marco Ferdeghini and Carlo Cavedon and Emanuele Zivelonghi and Riccardo Calandrino and A. Fenzi and Andrea Sbarbati and Federico Boschi},
  journal={Journal of Biomedical Optics},
  year={2013},
  volume={18}
}
Abstract. Cerenkov luminescence imaging is an emerging optical preclinical modality based on the detection of Cerenkov radiation induced by beta particles when traveling though biological tissues with a velocity greater than the speed of light. We present the first human Cerenkography obtained by detecting Cerenkov radiation escaping the thyroid gland of a patient treated for hyperthyroidism. The Cerenkov light was detected using an electron multiplied charge coupled device and a conventional C… 
Cerenkov luminescence imaging of human breast cancer: a Monte Carlo simulations study
Cerenkov luminescence imaging (CLI) is a novel molecular imaging technique based on the detection of Cerenkov light produced by beta particles traveling through biological tissues. In this paper we
Cerenkov Luminescence Imaging at a Glance
Cerenkov luminescence imaging (CLI) is a new technique that has rapidly gained great interest in the molecular imaging field bridging optical imaging and nuclear medicine. Based on the detection of
Three-Dimensional Quantitative Cerenkov Luminescence Imaging
Cerenkov luminescence imaging (CLI) is an up-and-coming optical technique for in vivo imaging of beta-emitting radioisotopes. CLI relies on measurements of the Cerenkov radiation emitted when
Computed Cerenkov luminescence yields for radionuclides used in biology and medicine.
TLDR
Using Monte Carlo simulations, forty-seven different radionuclides are studied and it is shown that Cerenkov light yields in tissue can be as high as a few tens of photons per nuclear decay for a wavelength range of 400-800 nm.
A Review of Recent and Emerging Approaches for the Clinical Application of Cerenkov Luminescence Imaging
Cerenkov luminescence is a blue-weighted emission of light produced by a vast array of clinically approved radioisotopes and LINAC accelerators. When β particles (emitted during the decay of
Innovations in Nuclear Imaging Instrumentation: Cerenkov Imaging.
TLDR
The fundamental breakthroughs and recent advances in reagents and instrumentation methods for CLI as well as therapeutic application of CL are covered.
Review of biomedical Čerenkov luminescence imaging applications.
TLDR
This review evaluates new improvements in Čerenkov Luminescence Imaging for both medical value and biological insight.
Real-time in vivo Cherenkoscopy imaging during external beam radiation therapy
TLDR
The first in vivo Cherenkov images of a real-time Cherenkoscopy during EBRT are presented and coregistration between photography and CherenKoscopy validated thatCherenkov photons were detected from the planned treatment region.
Cerenkov Luminescence Endoscopy: Improved Molecular Sensitivity with β−-Emitting Radiotracers
TLDR
This work investigated the improvement in the sensitivity of CLE brought about by using a β− radiotracer that improved Cerenkov signal due to both higher β-particle energy and lower γ noise in the imaging optics because of the lack of positron annihilation.
Cerenkov imaging.
TLDR
Smart imaging agents have been designed based on modulation of the Cerenkov signal using small molecules and nanoparticles giving better insight of the tumor biology, expanding the current range of applications.
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