First-generation fluoroquinolone use and subsequent emergence of multiple drug-resistant bacteria in the intensive care unit.

Abstract

OBJECTIVE The objective of this study was to determine the relationship between fluoroquinolone (FQ) use and subsequent emergence of multiple drug-resistant bacteria (MRB) in the intensive care unit (ICU). DESIGN The authors conducted a prospective observational cohort study and a case control study. SETTING The study was conducted in a 30-bed ICU… (More)

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