First-generation agents: aspirin, heparin and coumarins.

  • Richard Müller
  • Published 2004 in Best practice & research. Clinical haematology


Aspirin, heparin and the coumarins are the classical anti-thrombotic agents. They represent the platform upon which newer drugs holding the promise of greater efficacy and less toxicity are being developed. Even as such newer drugs arrive into clinical practice, the older agents remain remarkable for their decades-long pre-eminence. All derive from natural… (More)


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