First evidence for the presence of efflux pump in the earthworm Eisenia andrei.

@article{Hackenberger2012FirstEF,
  title={First evidence for the presence of efflux pump in the earthworm Eisenia andrei.},
  author={Branimir Kutuzovi{\'c} Hackenberger and Mirna Velki and Sandra Stepi{\'c} and Davorka K Hackenberger},
  journal={Ecotoxicology and environmental safety},
  year={2012},
  volume={75 1},
  pages={40-5}
}
Efflux pumps are transport proteins involved in the extrusion of toxic substrates from cells to the external environment. Activities of efflux pumps have been found in many organisms, however such activity has not been evidenced in earthworms. Adult Eisenia andrei earthworms were exposed to efflux modulators - verapamil (a known inhibitor of efflux pump protein) and dexamethasone (a known inducer of efflux activity) - and the amount of absorbed fluorescent dye rhodamine B was measured. The… CONTINUE READING

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