First evidence for homologous recombination-mediated large DNA inversion on the Bacillus subtilis 168 chromosome.

@article{Itaya1994FirstEF,
  title={First evidence for homologous recombination-mediated large DNA inversion on the Bacillus subtilis 168 chromosome.},
  author={Mitsuhiro Itaya},
  journal={Bioscience, biotechnology, and biochemistry},
  year={1994},
  volume={58 10},
  pages={1836-41}
}
  • Mitsuhiro Itaya
  • Published 1994 in Bioscience, biotechnology, and biochemistry
A Bacillus subtilis 168 strain carrying an inversion of about 1600 kb-long chromosomal DNA was isolated. Physical and genetic analyses demonstrated that the inversion was generated as a result of homologous recombination between two homologous sequences integrated at the met and leuB loci. This is the first clear evidence of a large stable chromosomal… CONTINUE READING