First evaluation of an improved assay for molecular genetic detection of tuberculosis as well as rifampin and isoniazid resistances.

@article{Crudu2012FirstEO,
  title={First evaluation of an improved assay for molecular genetic detection of tuberculosis as well as rifampin and isoniazid resistances.},
  author={Valeriu Crudu and Ecaterina Stratan and Elena Romancenco and Vera Allerheiligen and Andreas Hillemann and Nicolae Moraru},
  journal={Journal of clinical microbiology},
  year={2012},
  volume={50 4},
  pages={1264-9}
}
The commercially available line probe assay MTBDRplus 2.0 (Hain Lifescience, Nehren, Germany) was evaluated for its ability to detect Mycobacterium tuberculosis complex (MTBC) and mutations conferring resistance to rifampin (RMP) and isoniazid (INH) directly in smear-negative and smear-positive pulmonary clinical specimens under routine laboratory conditions. A total of 348 samples originating from Moldova, a high-incidence country for tuberculosis (TB), were investigated. Two hundred fifty… CONTINUE READING

6 Figures & Tables

Connections & Topics

Mentioned Connections BETA
First evaluation of an improved assay for molecular genetic detection of tuberculosis as well as rifampin and isoniazid resistances .
The commercially available line probe assay MTBDRplus 2.0 ( Hain Lifescience , Nehren , Germany ) was evaluated for its ability to detect Mycobacterium tuberculosis complex ( MTBC ) and mutations conferring resistance to rifampin ( RMP ) and isoniazid ( INH ) directly in smear - negative and smear - positive pulmonary clinical specimens under routine laboratory conditions .
The commercially available line probe assay MTBDRplus 2.0 ( Hain Lifescience , Nehren , Germany ) was evaluated for its ability to detect Mycobacterium tuberculosis complex ( MTBC ) and mutations conferring resistance to rifampin ( RMP ) and isoniazid ( INH ) directly in smear - negative and smear - positive pulmonary clinical specimens under routine laboratory conditions .
First evaluation of an improved assay for molecular genetic detection of tuberculosis as well as rifampin and isoniazid resistances .
The commercially available line probe assay MTBDRplus 2.0 ( Hain Lifescience , Nehren , Germany ) was evaluated for its ability to detect Mycobacterium tuberculosis complex ( MTBC ) and mutations conferring resistance to rifampin ( RMP ) and isoniazid ( INH ) directly in smear - negative and smear - positive pulmonary clinical specimens under routine laboratory conditions .
The commercially available line probe assay MTBDRplus 2.0 ( Hain Lifescience , Nehren , Germany ) was evaluated for its ability to detect Mycobacterium tuberculosis complex ( MTBC ) and mutations conferring resistance to rifampin ( RMP ) and isoniazid ( INH ) directly in smear - negative and smear - positive pulmonary clinical specimens under routine laboratory conditions .
All Topics