First-episode types in bipolar disorder: predictive associations with later illness.

  title={First-episode types in bipolar disorder: predictive associations with later illness.},
  author={Ross J. Baldessarini and Leonardo Tondo and Caterina Visioli},
  journal={Acta psychiatrica Scandinavica},
  volume={129 5},
OBJECTIVE Characteristics of initial illness in bipolar disorder (BD) may predict later morbidity. METHOD We reviewed computerized clinical records and life charts of DSM-IV-TR BD-I or BD-II patients at affiliated mood-disorder centers to ascertain relationships of initial major illnesses to later morbidity and other clinical characteristics. RESULTS Adult BD patient-subjects (N=1081; 59.8% BD-I; 58.1% women; 43% ever hospitalized) were followed 15.7±12.8 years after onsets ranking… CONTINUE READING
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