First deuterated drug approved

@article{Schmidt2017FirstDD,
  title={First deuterated drug approved},
  author={Charles Schmidt},
  journal={Nature Biotechnology},
  year={2017},
  volume={35},
  pages={493-494}
}
493 In April, the US Food and Drug Administration cleared the first deuterated drug, Austedo (deutetrabenazine), from Teva of Petach Tikva, Israel, for the treatment of Huntington’sdisease-related movement disorders. Austedo is also the first new treatment in over a decade for this indication. Deuteration has come in and out of fashion for more than 50 years and recently companies have started to pay big sums for heavy-hydrogen drugs. Teva acquired rights to Austedo through its $3.5-billion… Expand
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References

SHOWING 1-2 OF 2 REFERENCES
Effect of Deutetrabenazine on Chorea Among Patients With Huntington Disease: A Randomized Clinical Trial.
TLDR
Deutetrabenazine is a novel molecule containing deuterium, which attenuates CYP2D6 metabolism and increases active metabolite half-lives and may therefore lead to stable systemic exposure while preserving key pharmacological activity in patients with Huntington disease. Expand