First detection of genotype 3 hepatitis E virus RNA in river water in Cambodia.


To identify and describe hepatitis E virus (HEV) strains in aquatic environments in Cambodia, we collected two river-water samples from upstream and downstream sites along the Siem Reap River and examined them for HEV using a virus concentration method followed by TaqMan reverse transcription PCR and genetic analysis of the PCR product. Genotype 3 HEV strain was detected from the river-water sample collected from the river downstream, indicating that genotype 3 HEV strains are circulating in this region. To our knowledge, this is the first report demonstrating HEV contamination in aquatic environments in Cambodia.

DOI: 10.1016/j.trstmh.2009.04.004
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@article{Kitajima2009FirstDO, title={First detection of genotype 3 hepatitis E virus RNA in river water in Cambodia.}, author={Masaaki Kitajima and Koichi Matsubara and Sethy Sour and Eiji Haramoto and Hiroyuki Katayama and Shinichiro Ohgaki}, journal={Transactions of the Royal Society of Tropical Medicine and Hygiene}, year={2009}, volume={103 9}, pages={955-7} }