First detection of a carbapenem-hydrolyzing metalloenzyme in an Enterobacteriaceae isolate in France.

@article{Lartigue2004FirstDO,
  title={First detection of a carbapenem-hydrolyzing metalloenzyme in an Enterobacteriaceae isolate in France.},
  author={Marie-Fr{\'e}d{\'e}rique Lartigue and Laurent Poirel and Patrice L. Nordmann},
  journal={Antimicrobial agents and chemotherapy},
  year={2004},
  volume={48 12},
  pages={
          4929-30
        }
}
Although many β-lactamases with expanded spectra have been described for the Enterobacteriaceae, carbapenemases remain infrequent. Acquired carbapenemases of the metalloenzyme group (Ambler class B) are mostly either of the IMP or the VIM type. The VIM enzymes were reported first from Verona in Italy (VIM-1) and are scattered now in southern Europe, South America, and Southeast Asia (6). Our group had identified the first VIM enzyme (VIM-2) in France from Pseudomonas aeruginosa isolates (8… CONTINUE READING

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