First case of AML with rare chromosome translocations: a case report of twins

@inproceedings{Wang2018FirstCO,
  title={First case of AML with rare chromosome translocations: a case report of twins},
  author={Lin Wang and Yanhua Sun and Yanli Sun and Lingbin Meng and Xin Jian Xu},
  booktitle={BMC Cancer},
  year={2018}
}
Leukemia is different from solid tumor by harboring genetic rearrangements that predict prognosis and guide treatment strategy. PML-RARA, RUNX1-RUNX1T1, and KMT2A-rearrangement are common genetic rearrangements that drive the development of acute myeloid leukemia (AML). By contrast, rare genetic rearrangements may also contribute to leukemogenesis but are… CONTINUE READING