First blood vessels in the avian neural tube are formed by a combination of dorsal angioblast immigration and ventral sprouting of endothelial cells.

@article{Kurz1996FirstBV,
  title={First blood vessels in the avian neural tube are formed by a combination of dorsal angioblast immigration and ventral sprouting of endothelial cells.},
  author={Haymo Kurz and Tara Gaertner and Peter S. Eggli and B. G. Christ},
  journal={Developmental biology},
  year={1996},
  volume={173 1},
  pages={133-47}
}
We studied the early pattern of neural tube (NT) vascularization in quail embryos and chick-quail chimeras. Angioblasts appeared first in the dorsal third at Hamburger and Hamilton (HH) stage 19 as single, migrating cells. Their distribution did not correspond to a segmental pattern. After this initial dorsal immigration, endothelial sprouts invaded the NT on either side of the floor plate (HH stage 21). These cells remained continuous with their arterial vascular sources, connected to the… CONTINUE READING
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