First- and second-line drug resistance patterns among previously treated tuberculosis patients in India.

@article{Paramasivan2010FirstAS,
  title={First- and second-line drug resistance patterns among previously treated tuberculosis patients in India.},
  author={Chinnambedu Nainarappan Paramasivan and Fathima Rehman and Fraser Wares and N Sundar Mohan and Shyam Sundar and Santha Devi and P. R. Narayanan},
  journal={The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease},
  year={2010},
  volume={14 2},
  pages={243-6}
}
Culture and drug susceptibility testing results of 2816 tuberculosis (TB) patients from across India who had failed repeated treatments from 2001 to 2004 were retrospectively analysed at the Tuberculosis Research Centre, Chennai. Of 1498 (53%) identified as having multidrug-resistant TB (MDR-TB), 671 (44.8%) were resistant to > or =1 second-line drugs (SLDs): 490 (32.7%) to ethionamide, 245 (16.4%) to ofloxacin and 169 (11.3%) to kanamycin; 69 (4.6%) were extensively drug-resistant TB (XDR-TB… CONTINUE READING

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