First- and second-generation perfluorocarbon emulsions

  title={First- and second-generation perfluorocarbon emulsions},
  author={S. I. Vorob’ev},
  journal={Pharmaceutical Chemistry Journal},
This review addresses first- and second-generation perfluorocarbon emulsions, which are used as blood substitutes when the use of donor blood is problematic. The first perfluorocarbon preparations created as synthetic blood substitutes started to be used in Japan (Green Cross Corporation). These were the first-generation preparations Fluosol-DA 20%, Fluosol-DA 35%, and the Russian formulation Perftoran. The disadvantages of first-generation perfluorocarbon preparations were that they could not… Expand

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