First Trial of CRISPR-Edited T cells in Lung Cancer.

@article{Lacey2020FirstTO,
  title={First Trial of CRISPR-Edited T cells in Lung Cancer.},
  author={Simon F. Lacey and Joseph A. Fraietta},
  journal={Trends in molecular medicine},
  year={2020}
}
Targeting Cancer with CRISPR/Cas9-Based Therapy
TLDR
Recent advancements in cancer-selective treatments based on the CRISPR/Cas9 system are described, especially focusing on strategies for targeted delivery of the CRisPR/cas9 machinery to affected cells, controlling Cas9 expression in tissues of interest and disrupting cancer-specific genes to result in selective death of malignant cells.
The Potential of CRISPR-Guided Therapies in the Dermatology Clinic
Effect of CRISPR/Cas9-Edited PD-1/PD-L1 on Tumor Immunity and Immunotherapy
TLDR
The recent progress in exploring the regulatory mechanism of tumor immune PD-1 and programmed death ligand 1(PD-L1) based on CRISPR/Cas9 technology and its clinical application in different cancer types are summarized.
Epigenetic Alterations and Inflammation as Emerging Use for the Advancement of Treatment in Non-Small Cell Lung Cancer
TLDR
Investigation on such topic is most likely to shed light on the molecular and immunological mechanisms of epigenetic and inflammatory factors and promote the application of epigenetics in the innovative diagnostic and therapeutic strategies for NSCLC.

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