Fir honeydew honey flavonoids inhibit TNF-α-induced MMP-9 expression in human keratinocytes: a new action of honey in wound healing

@article{Majtan2013FirHH,
  title={Fir honeydew honey flavonoids inhibit TNF-α-induced MMP-9 expression in human keratinocytes: a new action of honey in wound healing},
  author={Juraj Majtan and Jana Bohov{\'a} and Roc{\'i}o Garc{\'i}a-Villalba and Francisco Tom{\'a}s Barber{\'a}n and Zuzana Madakova and Tomas Majtan and Viktor Majt{\'a}n and Jaroslav Klaudiny},
  journal={Archives of Dermatological Research},
  year={2013},
  volume={305},
  pages={619-627}
}
Matrix metalloproteinase-9 (MMP-9) appears to be a major protease responsible for the degradation of matrix and growth-promoting agents in chronic wounds. Honey has been successfully used for treating non-healing wounds associated with infections. However, the mechanisms of its action at the cellular level have remained poorly understood. The aim of this study was to investigate the effect of fir honeydew honey on TNF-α-induced MMP-9 expression and secretion from human keratinocytes (HaCaT) and… CONTINUE READING