Fine tuning the inhibition profile of cyclosporine A by derivatization of the MeBmt residue.

@article{Prell2013FineTT,
  title={Fine tuning the inhibition profile of cyclosporine A by derivatization of the MeBmt residue.},
  author={E. A. Fehrenbach Prell and Viktoria Kahlert and Karl Peter Ruecknagel and Miroslav Male{\vs}evi{\'c} and Gunter Fischer},
  journal={Chembiochem : a European journal of chemical biology},
  year={2013},
  volume={14 1},
  pages={
          63-5
        }
}
Unique respect: The biological properties of four CsA derivatives were fine-tuned by tractable modifications of the MeBmt residue. The new CsA derivatives share strong inhibitory activity toward cyclophilins (Cyps), but each is unique with respect to immunosuppressive action and cellular localization. These CsA analogues can be used to study the physiological roles of extracellular Cyps. 
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