Fine-tuning neutrophil activation: Strategies and consequences.

@article{Linden2016FinetuningNA,
  title={Fine-tuning neutrophil activation: Strategies and consequences.},
  author={Maarten van der Linden and Linde Meyaard},
  journal={Immunology letters},
  year={2016},
  volume={178},
  pages={
          3-9
        }
}
In spite of their important role in host defense, neutrophils can also cause severe morbidity and mortality. Neutrophils have an extensive armory necessary to eradicate pathogens, but neutrophil infiltration and activation also induces major tissue injury associated with acute and chronic inflammatory disorders. Here, we review neutrophil anti-microbial functions and discuss their individual contribution to disease pathogenesis. Furthermore, we provide an overview of the anti-inflammatory drugs… CONTINUE READING
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