Fine structural mapping of a critical NH2-terminal region of p60src.

@article{Pellman1985FineSM,
  title={Fine structural mapping of a critical NH2-terminal region of p60src.},
  author={David S Pellman and Ellen A. Garber and Frederick R Cross and Hidesaburo Hanafusa},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1985},
  volume={82 6},
  pages={1623-7}
}
We have recently demonstrated that an NH2-terminal sequence required for myristylation and membrane association of the Rous sarcoma virus transforming protein, p60src, is contained within amino acids 2-14 [Cross, F.R., Garber, E. A., Pellman, D. & Hanafusa, H. (1984) Mol. Cell. Biol. 4, 1834-1842]. This sequence is also required for cell transformation. We have now constructed five mutants of Rous sarcoma virus that contain alterations in the src sequence coding for these 14 amino acids… CONTINUE READING
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