Fine mapping of the crossover-sites in theC4-H-2D region ofH-2 recombinant mouse strains

@article{Snoek1991FineMO,
  title={Fine mapping of the crossover-sites in theC4-H-2D region ofH-2 recombinant mouse strains},
  author={Margriet Snoek and Peter J. van Coeverden de Groot and Thomas Spiest and Robert D. Campbell and Peter Demand},
  journal={Immunogenetics},
  year={1991},
  volume={34},
  pages={409-412}
}
The class I and class II regions of the major histocompatibility complex (MHC) encode polymorphic molecules that present antigen to the T-cell receptor. The class HI region which lies between the class I and class II region contains genes for complement components (C4, Bf, and C2) and steroid 21 hydroxylase (21-OHA and B). This stretch of DNA of the class 11I region encompasses approximately 1100 kilobases (kb) in human and mouse (Dunham et al. 1987; Carrol et al. 1987; Miiller et al. 1987a… CONTINUE READING