Fine mapping of Ekp-1, a locus associated with silkworm (Bombyx mori) proleg development

@article{Xiang2008FineMO,
  title={Fine mapping of Ekp-1, a locus associated with silkworm (Bombyx mori) proleg development},
  author={Hui Xiang and Mai-He Li and Feng-tang Yang and Qiuhong Guo and Shuai Zhan and Haoran Lin and Xuexia Miao and Yuchen Huang},
  journal={Heredity},
  year={2008},
  volume={100},
  pages={533-540}
}
The silkworm homeotic mutant Ekp has a pair of rudimentary abdominal legs, called prolegs, in its A2 segment. This phenotype is caused by a single dominant mutation at the Ekp-1 locus, which was previously mapped to chromosome 6. To explore the possible association of Hox genes with proleg development in the silkworm, a map-based cloning strategy was used to isolate the Ekp-1 locus. Five Ekp-1-linked simple sequence repeat markers on chromosome 6 were used to generate a low-resolution map with… CONTINUE READING

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