Fine analysis of recognition sites of monoclonal antibodies, 1B7 and 1E4, using L cell transfectants of recombinant mouse MHC class II genes.

Abstract

Recognition sites of two monoclonal antibodies (mAbs), 1B7 and 1E4, specific for murine MHC class II were determined, using eleven L cell transfectants which express recombinant class II (I-A) molecules. 1B7 positive cells possessed a haplotype k in the alpha-helix of the beta-chain, whereas 1E4 positive cells had haplotype b at the alpha-helix of the beta… (More)

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