Fine Tuning and Cross-talking of TGF-β Signal by Inhibitory Smads

@inproceedings{Park2005FineTA,
  title={Fine Tuning and Cross-talking of TGF-β Signal by Inhibitory Smads},
  author={Seok Hee Park},
  year={2005}
}
Transforming Growth Factor (TGF)-β family, including TGF-β, bone morphorgenic protein (BMP), and activn, plays an important role in essential cellular functions such as proliferation, differentiation, apoptosis, tissue remodeling, angiognesis, immune responses, and cell adhesions. TGF-β predominantly transmits the signals through serine/ threonine receptor kinases and cytoplasmic proteins called Smads. Since the discovery of TGF-β in the early 1980s, the dysregulation of TGF-β/Smad signaling… CONTINUE READING
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