Finding the sources of missing heritability in a yeast cross


For many traits, including susceptibility to common diseases in humans, causal loci uncovered by genetic-mapping studies explain only a minority of the heritable contribution to trait variation. Multiple explanations for this ‘missing heritability’ have been proposed. Here we use a large cross between two yeast strains to accurately estimate different… (More)
DOI: 10.1038/nature11867


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