Finding the right niche: B-cell migration in the early phases of T-dependent antibody responses.

@article{Pereira2010FindingTR,
  title={Finding the right niche: B-cell migration in the early phases of T-dependent antibody responses.},
  author={Jo{\~a}o Pedro D. Pereira and Lisa M. Kelly and Jason G Cyster},
  journal={International immunology},
  year={2010},
  volume={22 6},
  pages={413-9}
}
Humoral immune responses depend on B cells encountering antigen, interacting with helper T cells, proliferating and differentiating into low-affinity plasma cells or, after organizing into a germinal center (GC), high-affinity plasma cells and memory B cells. Remarkably, each of these events occurs in association with distinct stromal cells in separate subcompartments of the lymphoid tissue. B cells must migrate from niche to niche in a rapid and highly regulated manner to successfully mount a… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 81 extracted citations

Intravital Imaging of Dynamic Bone and Immune Systems

Methods in Molecular Biology • 2018
View 15 Excerpts
Highly Influenced

B Cell Receptor Signaling

Methods in Molecular Biology • 2018
View 5 Excerpts
Highly Influenced

High-Speed Single-Molecule Tracking of CXCL13 in the B-Follicle

Front. Immunol. • 2018
View 4 Excerpts
Highly Influenced

Atypical chemokine receptor 4 shapes activated B cell fate

The Journal of experimental medicine • 2018
View 3 Excerpts

References

Publications referenced by this paper.
Showing 1-10 of 70 references

Antigens in immunity . XV . Ultrastructural features of antigen capture in primary and secondary lymphoid follicles

F. D. Batista, N. E. Harwood
J . Exp . Med . • 2009

Similar Papers

Loading similar papers…