Finding the rhythm of sudden cardiac death: new opportunities using induced pluripotent stem cell-derived cardiomyocytes.

@article{Sallam2015FindingTR,
  title={Finding the rhythm of sudden cardiac death: new opportunities using induced pluripotent stem cell-derived cardiomyocytes.},
  author={Karim Sallam and Yingxin Li and Philip T. Sager and Steven R. Houser and Joseph C. Wu},
  journal={Circulation research},
  year={2015},
  volume={116 12},
  pages={
          1989-2004
        }
}
Sudden cardiac death is a common cause of death in patients with structural heart disease, genetic mutations, or acquired disorders affecting cardiac ion channels. A wide range of platforms exist to model and study disorders associated with sudden cardiac death. Human clinical studies are cumbersome and are thwarted by the extent of investigation that can be performed on human subjects. Animal models are limited by their degree of homology to human cardiac electrophysiology, including ion… 

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