Finding large domains of similarly expressed genes

@article{Nicorici2006FindingLD,
  title={Finding large domains of similarly expressed genes},
  author={Daniel Nicorici and Olli P. Yli-Harja and Jaakko Astola},
  journal={IEEE Engineering in Medicine and Biology Magazine},
  year={2006},
  volume={25},
  pages={82-89}
}
In this study, a new method for finding and defining large domains of adjacent genes on a chromosome with similar expression profiles was introduced based on the use of the minimum description length (MDL) principle and the recursive segmentation procedure. For the recursive segmentation, a newly introduced stopping criterion using the MDL principle was used. Together they offer a novel method to view the large domains of similarly expressed genes in genome data. The description of the genome… CONTINUE READING