Finding gastric cancer related genes and clinical biomarkers for detection based on gene-gene interaction network.

@article{Wu2016FindingGC,
  title={Finding gastric cancer related genes and clinical biomarkers for detection based on gene-gene interaction network.},
  author={Xuesong Wu and Haoran Tang and Aoran Guan and Feng Sun and Hui Wang and Jie Shu},
  journal={Mathematical biosciences},
  year={2016},
  volume={276},
  pages={1-7}
}
BACKGROUND/OBJECTIVE Gastric cancer (GC) is the second leading cause of death resulted from cancer globally. The most common cause of GC is the infection of Helicobacter pylori, approximately 11% of cases are caused by genetic factors. The objective of this study was to develop an effective computational method to meaningfully interpret these GC-related genes and to predict potential prognostic genes for clinical detection. METHODS We employed the shortest path algorithm and permutation test… CONTINUE READING
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