Finding common protein interaction patterns across organisms

  title={Finding common protein interaction patterns across organisms},
  author={Mirco Gerke and Erich Bornberg-Bauer and Xiaoyi Jiang and Georg Fuellen},
  booktitle={Evolutionary bioinformatics online},
Protein interactions are an important resource to obtain an understanding of cell function. Recently, researchers have compared networks of interactions in order to understand network evolution. While current methods first infer homologs and then compare topologies, we here present a method which first searches for interesting topologies and then looks for homologs. PINA (protein interaction network analysis) takes the protein interaction networks of two organisms, scans both networks for… CONTINUE READING

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