Finding an "Achilles' heel" of cancer: the role of glucose and glutamine metabolism in the survival of transformed cells.

@article{Yuneva2008FindingA,
  title={Finding an "Achilles' heel" of cancer: the role of glucose and glutamine metabolism in the survival of transformed cells.},
  author={Mariia O Yuneva},
  journal={Cell cycle},
  year={2008},
  volume={7 14},
  pages={2083-9}
}
Multiple lines of evidence indicate that the process of tumorigenesis is often associated with altered metabolism of two major nutrients, glucose and glutamine. These two nutrients are engaged in multiple metabolic pathways that can be required for cell viability. The roles of glucose and glutamine in the survival of transformed cells both in vitro and in vivo have been separately evaluated in various cell systems, and glucose as the major cellular energy source has received most of the… CONTINUE READING

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