Finding New Genes for Non-Syndromic Hearing Loss through an In Silico Prioritization Study

@inproceedings{Accetturo2010FindingNG,
  title={Finding New Genes for Non-Syndromic Hearing Loss through an In Silico Prioritization Study},
  author={Matteo Accetturo and Teresa Maria Creanza and Claudia Santoro and Giancarlo Tria and Antonio Giordano and Simone Battagliero and Antonella Vaccina and Gaetano Scioscia and Pietro Leo},
  booktitle={PloS one},
  year={2010}
}
At present, 51 genes are already known to be responsible for Non-Syndromic hereditary Hearing Loss (NSHL), but the knowledge of 121 NSHL-linked chromosomal regions brings to the hypothesis that a number of disease genes have still to be uncovered. To help scientists to find new NSHL genes, we built a gene-scoring system, integrating Gene Ontology, NCBI Gene and Map Viewer databases, which prioritizes the candidate genes according to their probability to cause NSHL. We defined a set of… CONTINUE READING
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Gene Expression Omnibus Database

  • GEO NCBI
  • Available: http://www. ncbi.nlm.nih.gov/gds…
  • 2010
1 Excerpt

Organized view of the transcriptome

  • NCBI UniGene
  • Available: http:// www.ncbi.nlm.nih.gov/unigene…
  • 2010
1 Excerpt

Mutations in the seed region of human miR-96 are responsible for nonsyndromic progressive hearing loss

  • A Mencı́a, S Modamio-Høybjør, N Redshaw, M Morı́n, F Mayo-Merino
  • Nat Genet
  • 2009
1 Excerpt

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