Corpus ID: 23615481

Finasteride treatment and neuroactive steroid formation.

  title={Finasteride treatment and neuroactive steroid formation.},
  author={M. Du{\vs}kov{\'a} and M. Hill and M. Hanu{\vs} and M. Matouskov{\'a} and Ľ. St{\'a}rka},
  journal={Prague medical report},
  volume={110 3},
  • M. Dušková, M. Hill, +2 authors Ľ. Stárka
  • Published 2009
  • Medicine
  • Prague medical report
  • Finasteride is the 5alpha-reductase inhibitor that received clinical approval for the treatment of human benign prostate hyperplasia and androgenetic alopecia. The 5alpha-reductase is enzyme responsible for the reduction of testosterone to dihydrostestosterone, progesterone to dihydroprogesterone and deoxycorticosterone to dihydrodeoxycorticosterone, steroids modulating the action of gamma-aminobutyric acid on GABA receptors. These neuroactive steroids possess anticonvulsant, antidepressant and… CONTINUE READING
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