Finasteride in the treatment of men with androgenetic alopecia. Finasteride Male Pattern Hair Loss Study Group.

  title={Finasteride in the treatment of men with androgenetic alopecia. Finasteride Male Pattern Hair Loss Study Group.},
  author={Keith D. Kaufman and Elise A. Olsen and Demian Whiting and Roxana Savin and Richard L Devillez and Wilma Fowler Bergfeld and Vera H. Price and Dominique Van Neste and Janet L Roberts and Maria K. Hordinsky and Jonathan H. Shapiro and Bruce Binkowitz and Gleen J Gormley},
  journal={Journal of the American Academy of Dermatology},
  volume={39 4 Pt 1},
BACKGROUND Androgenetic alopecia (male pattern hair loss) is caused by androgen-dependent miniaturization of scalp hair follicles, with scalp dihydrotestosterone (DHT) implicated as a contributing cause. Finasteride, an inhibitor of type II 5alpha-reductase, decreases serum and scalp DHT by inhibiting conversion of testosterone to DHT. OBJECTIVE Our purpose was to determine whether finasteride treatment leads to clinical improvement in men with male pattern hair loss. METHODS In two 1-year… CONTINUE READING
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