Finasteride in the treatment of alopecia

  title={Finasteride in the treatment of alopecia},
  author={J. Libecco and W. Bergfeld},
  journal={Expert Opinion on Pharmacotherapy},
  pages={933 - 940}
  • J. Libecco, W. Bergfeld
  • Published 2004
  • Medicine
  • Expert Opinion on Pharmacotherapy
  • Finasteride is a 5α-reductase inhibitor approved for the treatment of male pattern hair loss. Originally approved for the treatment of benign prostatic hypertrophy in 1992, its approval was expanded in 1997 to include the treatment of androgenetic alopecia (AGA) in men at a dose of 1 mg/day. Finasteride inhibits 5α-reductase, thereby prohibiting the conversion of testosterone to dihydrotestosterone (DHT), which is implicated in the development of hairless in some men. Reduction in DHT results… CONTINUE READING
    69 Citations
    A new look at the 5alpha-reductase inhibitor finasteride.
    • 113
    Beyond testosterone cypionate: evidence behind the use of nandrolone in male health and wellness
    • 5
    • PDF
    Actions of 5α-reductase inhibitors on the epididymis
    • 36
    • PDF
    Design of Finasteride-Loaded Nanoparticles for Potential Treatment of Alopecia
    • 23
    Effect of Pumpkin Seed Oil on Hair Growth in Men with Androgenetic Alopecia: A Randomized, Double-Blind, Placebo-Controlled Trial
    • 27
    • PDF
    Adverse effects of 5α-reductase inhibitors: What do we know, don’t know, and need to know?
    • 56


    Lack of efficacy of finasteride in postmenopausal women with androgenetic alopecia.
    • 217
    Finasteride in the treatment of men with androgenetic alopecia. Finasteride Male Pattern Hair Loss Study Group.
    • 493
    Finasteride in the treatment of men with frontal male pattern hair loss.
    • 173
    • PDF
    Hair loss in women with hyperandrogenism: four cases responding to finasteride.
    • 85
    Finasteride in the treatment of hirsutism: new therapeutic perspectives.
    • 48
    Clinical and hormonal effects of the 5 alpha-reductase inhibitor finasteride in idiopathic hirsutism.
    • 52
    Chronic treatment with finasteride daily does not affect spermatogenesis or semen production in young men.
    • 103