Final height after treatment for childhood acute lymphoblastic leukemia: comparison of no cranial irradiation with 1800 and 2400 centigrays of cranial irradiation.

@article{Sklar1993FinalHA,
  title={Final height after treatment for childhood acute lymphoblastic leukemia: comparison of no cranial irradiation with 1800 and 2400 centigrays of cranial irradiation.},
  author={Charles A. Sklar and Ann C Mertens and Andreas Walter and David Andrew Mitchell and Mark E. Nesbit and Maura C O'Leary and Raymond Hutchinson and Anna T. Meadows and Leslie L. Robison},
  journal={The Journal of pediatrics},
  year={1993},
  volume={123 1},
  pages={
          59-64
        }
}
We analyzed growth and final heights in 127 patients (68 female patients) treated for childhood acute lymphoblastic leukemia. Central nervous system prophylaxis included either no cranial radiation therapy (CRT) (n = 38), irradiation with 1800 centigrays (cGy) (n = 36), or irradiation with 2400 cGy (n = 53). None of the patients received spinal irradiation. Mean (+/- SEM) age at diagnosis was 6.4 +/- 0.25 years, mean height standard deviation score (SDS) at diagnosis was 0.28 +/- 0.12, and mean… CONTINUE READING