Final Report on the Safety Assessment of PPG-2 Methyl Ether, PPG-3 Methyl Ether, and PPG-2 Methyl Ether Acetate

  title={Final Report on the Safety Assessment of PPG-2 Methyl Ether, PPG-3 Methyl Ether, and PPG-2 Methyl Ether Acetate},
  author={Valerie C. Robinson and Wilma Fowler Bergfeld and Donald V. Belsito and Curtis D. Klaassen and James G. Marks and Ronald C. Shank and Thomas J. Slaga and Paul W. Snyder and F. Alan Andersen},
  journal={International Journal of Toxicology},
  pages={162S - 174S}
PPG-2 methyl ether, PPG-3 methyl ether, and PPG-2 methyl ether acetate are used in cosmetics as fragrance ingredients and/or solvents at concentrations of 0.4% to 2%. Propylene glycol ethers are rapidly absorbed and distributed throughout the body when introduced by inhalation or oral exposure, but the inhalation toxicity of PPG-2 methyl ether vapor, for example, is low. Aerosols, such as found with hair sprays, produce particle sizes that are not respirable. Because these ingredients are… 
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