Filtration Parameters Influencing Circulating Tumor Cell Enrichment from Whole Blood

  title={Filtration Parameters Influencing Circulating Tumor Cell Enrichment from Whole Blood},
  author={Frank A. W. Coumans and Guus van Dalum and Markus Beck and Leon W. M. M. Terstappen},
  booktitle={PloS one},
Filtration can achieve circulating tumor cell (CTC) enrichment from blood. Key parameters such as flow-rate, applied pressure, and fixation, vary largely between assays and their influence is not well understood. Here, we used a filtration system, to monitor these parameters and determine their relationships. Whole blood, or its components, with and without spiked tumor cells were filtered through track-etched filters. We characterize cells passing through filter pores by their apparent… CONTINUE READING
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Detection and characterization of Circulating Tumor Cells by the Cell Search approach. Methods in Molecular Biology - Circulating Tumour Cells

  • Coumans FAW, Terstappen
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1 Excerpt

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Isolation of Circulating Tumor Cells by Size Exclusion using Lithography Fabricated Precision Microfilters

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