Filtration Parameters Influencing Circulating Tumor Cell Enrichment from Whole Blood

@inproceedings{Coumans2013FiltrationPI,
  title={Filtration Parameters Influencing Circulating Tumor Cell Enrichment from Whole Blood},
  author={Frank A. W. Coumans and Guus van Dalum and Markus Beck and Leon W. M. M. Terstappen},
  booktitle={PloS one},
  year={2013}
}
Filtration can achieve circulating tumor cell (CTC) enrichment from blood. Key parameters such as flow-rate, applied pressure, and fixation, vary largely between assays and their influence is not well understood. Here, we used a filtration system, to monitor these parameters and determine their relationships. Whole blood, or its components, with and without spiked tumor cells were filtered through track-etched filters. We characterize cells passing through filter pores by their apparent… CONTINUE READING
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Detection and characterization of Circulating Tumor Cells by the Cell Search approach. Methods in Molecular Biology - Circulating Tumour Cells

  • Coumans FAW, Terstappen
  • LWMM
  • 2013
1 Excerpt

Challenges in the Enumeration and Phenotyping of CTC

  • Coumans FAW, ST Ligthart, JW Uhr, Terstappen LWMM
  • Clin Cancer Res
  • 2012

Isolation of Circulating Tumor Cells by Size Exclusion using Lithography Fabricated Precision Microfilters

  • D Adams, O Makarova, P Zhu, S Li, PT Amstutz
  • 2011

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