Filopodia rotate and coil by actively generating twist in their actin shaft

  title={Filopodia rotate and coil by actively generating twist in their actin shaft},
  author={Natascha Leijnse and Younes F Barooji and Mohammad Reza Arastoo and Stine Lauritzen S{\o}nder and Bram Verhagen and Lena Wullkopf and Janine Terra Erler and Szabolcs Semsey and Jesper Nylandsted and Lene Broeng Oddershede and Amin Doostmohammadi and Poul Martin Bendix},
  journal={Nature Communications},
Filopodia are actin-rich structures, present on the surface of eukaryotic cells. These structures play a pivotal role by allowing cells to explore their environment, generate mechanical forces or perform chemical signaling. Their complex dynamics includes buckling, pulling, length and shape changes. We show that filopodia additionally explore their 3D extracellular space by combining growth and shrinking with axial twisting and buckling. Importantly, the actin core inside filopodia performs a… 


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